The Ionization of Calcium, Magnesium, and Strontium Citrates*
نویسندگان
چکیده
Since the postulation by Greenwald (1) of a citrate-like substance in blood, capable of holding calcium in a non-ionized form, the behavior of calcium in the presence of citrate has received considerable attention from investigators primarily interested in the state of calcium in the living organism. The subject has also assumed considerable importance in the field of the chemistry of milk. The hypothesis that citrate forms a complex ion with calcium, invoked by Sabbatani (2) in 1901 to explain the effect of citrate in preventing the coagulation of blood, has received support from the work of Shear and Kramer (3), Shear, Kramer, and Resnikoff (4), Greenberg and Greenberg (5), Hastings, Murray, and Sendroy (6), Clark, Percival, and Stewart (7), Shelling and Maslow (8), Peretti (9), Minot, Dodd, and Bryan (lo), Mulli and Standenath (ll), and others. On the other hand, Salant and Hecht (12) and Salant and Swanson (13) failed to find support for this hypothesis in certain biological experiments. Previous investigations have failed to lead to definite conclusions as to the nature of the reaction occurring between calcium and citrate in solution, and have furnished insufficient information for a quantitative analysis of this reaction, owing chiefly to the fact that no satisfactory method for the direct observation of calcium ion concentrations has been available. A new approach
منابع مشابه
Effects of chemical speciation on the mineralization of organic compounds by microorganisms.
The mineralization of 1.0 to 100 ng each of four complexing compounds-oxalate, citrate, nitrilotriacetate (NTA), and EDTA-per ml was tested in media prepared in accordance with equilibrium calculations by a computer program so that the H, Ca, Mg, Fe, or Al complex (chemical species) was predominant. Sewage microorganisms mineralized calcium citrate more rapidly than iron, aluminum, or hydrogen ...
متن کاملInhibitory effects of citrates in the determination of trace amounts of penicillin.
In the microbiological assay for the determination of trace amounts of penicillin, it has been shown that sodium citrate and penicillin act synergistically against Sarcina lutea. The inhibitory action of citrate appears to involve a sequestering of divalent cations essential to the growth of the organism as shown by minimal inhibitory concentration and agar diffusion studies. The addition of ca...
متن کاملVitamin D and magnesium absorption in man.
1. The effects of vitamin D and its hydroxylated derivatives on calcium and magnesium absorption have been examined in 47 balance studies on patients with various disorders of calcium or bone metabolism. 2. Vitamin D significantly increased the mean net absorption of calcium and also the calcium balance. The mean net absorption of magnesium was also significantly increased although the rise was...
متن کاملDetermination of trace magnesium and strontium in calcium carbonate and calcareous skeletons of marine planktonic organisms using high performance chelation ion chromatography
متن کامل
Precipitation of Calcium, Magnesium, Strontium and Barium in Tissues of Four Acacia Species (Leguminosae: Mimosoideae)
Precipitation of calcium in plants is common. There are abundant studies on the uptake and content of magnesium, strontium and barium, which have similar chemical properties to calcium, in comparison with those of calcium in plants, but studies on co-precipitation of these elements with calcium in plants are rare. In this study, we compared morphologies, distributional patterns, and elemental c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003